Toprazole 40 Mg - 30 Tabs

Product Name

• Toprazole 40 Mg, Reduce Stomach Acidity & Relief Heartburn - 30 Tablets

Scientific Name

• Pantoprazole 40 Mg Tablets

Category Of Toprazole 40 Mg Tablets

• Heartburn Drugs

Mechanism Of Action Of Pantoprazole

• Hydrochloric acid (HCl) secretion into the gastric lumen is a process regulated mainly by the H (+)/K (+)-ATPase of the proton pump, expressed in high quantities by the parietal cells of the stomach.
• proton pump inhibitor that inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium (H+/K+-exchanging ATPase), the “proton pump” of the gastric parietal cell.
• Pantoprazole is a member of a class called “proton pump inhibitors”

Therapeutic Indications Of Toprazole 40 Mg Tablets

• Duodenal ulcers (a sore that forms at the beginning of your small intestine)
• H Pylori eradication (bacteria that can live in your gut and cause ulcers) to prevent recurrence of duodenal ulcers
• Benign gastric ulcer (a non-cancerous sore that forms in your stomach)
• NSAID-associated ulcer (sore that forms in your gut due to excessive use of NSAIDs)
• GERD (acid reflux also known as “heartburn”): is the backflow of acid from the stomach into the gullet (“food pipe”) which may become inflamed and painful. This may cause your symptoms such as a painful sensation in the chest rising up to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
• Erosive esophagitis (acid irritation injuring the esophagus): inflammation that may damage tissues of the esophagus, the muscular tube that delivers food from your mouth to your stomach. Esophagitis can cause painful, difficult swallowing and chest pain.
• Pathological hyper-secretory conditions (problems in the gut that cause excessive acid production)

Method Of Administration Of Toprazole 40 Mg Tablets

• Adults: The recommended dose is one tablet (20 mg) orally every day.
• Children: The safety and effectiveness of this medication have not been established yet in children.
• Take this medication as recommended or as recommended by your doctor or pharmacist.
• Make sure to take this medication for at least 2-3 consecutive days.
• Stop taking this medication when you feel completely relieved from your symptoms.
• Do not take the medication for more than 4 weeks if not recommended by your doctor.
• Take the tablet before a meal.
• Take the medication at the same time every day.
• Swallow tablet whole with a glass of water.
• Do not break or chew the tablet.
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Toprazole 40 Mg Tablets

• Although it may be rare, some patients may experience undesirable side effects when taking a medication. Tell your doctor or get medical help right away and stop the medication if you have any of the following signs or symptoms:
• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of serious skin reactions, like, bleeding and losing skin around genitals, nose, mouth, or eyes, blistering or peeling of the skin, rash with swelling, and rash upon sun exposure.
• Signs of liver damage, like, yellowing of the eyes and skin.
• Signs of kidney damage, like lower back pain with fever and painful urination.
• Common side effects: Benign polyps in the stomach.
• Uncommon or rare side effects: Headache, diarrhea, feeling sick, flatulence, vomiting, bloating, dry mouth, dizziness, constipation

Pregnancy & Breastfeeding Precautions While Taking Toprazole 40 Mg Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Heartburn

• Eat sparingly and slowly
• Avoid certain foods like (Fried food, Chili foods, …etc.)
• Don't drink carbonated beverages
• Stay up after eating & Finish eating three hours before you go to bed
• Don't move too fast
• Sleep on an incline
• Lose weight if it's advised
• Avoid tight clothes
• If you smoke, quit
• Remember you can always check for H-Pylori Infection by using Heli C Check, H. Pylori Self-Testing Device

Warnings & Special Precautions while Taking Toprazole 40 Mg Tablets

• Talk to your doctor or pharmacist if you develop allergic reactions to this medication or have previously experienced allergic reactions to medications that are similar to this one (proton pump inhibitors). Signs of allergic reactions include shortness of breath, skin rash, swelling of the face or neck, decreased blood pressure and dizziness.
• Make sure to tell your doctor if you have liver problems, jaundice (yellowing of eyes and skin), anemia, bleeding in your stomach or bowel, unintentional weight loss, difficulty swallowing, persistent vomiting or vomiting with blood, and any other medical problem.
• Make sure to tell your doctor if you previously have had a stomach ulcer (sore in your stomach) or surgery in your stomach or bowel.
• Consult your doctor if you are placed on continuous symptomatic treatment of heartburn or indigestion for 4 weeks or more.
• Make sure to tell your doctor if your symptoms are new or have recently changed and you are aged more than 55 years.
• Make sure to follow up with your doctor on a regular basis if you are aged more than 55 years and are taking non-prescription heartburn medications almost every day.
• Consult your doctor if you will be undergoing an endoscopy or urea breath test before starting the medication.
• This medication may not cause immediate relief after taking it. It is expected to start working after 1 day of treatment and up to 7 days for complete relief.
• Tell your doctor or pharmacist if you are taking:

1. If you are taking some antifungals like ketoconazole (used to treat fungal infections).
2. If you are taking HIV protease inhibitors (medications used to treat HIV), like, atazanavir and
3. If you are taking warfarin or phenprocoumon (blood thinners).
4. If you are taking methotrexate (used to treat rheumatoid arthritis, psoriasis, and cancer).
5. If you are taking other acid-reducing medications, like, another proton pump inhibitor (e.g. lansoprazole, omeprazole, rabeprazole) or an H2 antagonist (e.g. famotidine, ranitidine).
6. Antacids (e.g. alginic acid, magaldrate, aluminum hydroxide, sodium bicarbonate, magnesium carbonate, or combinations) may be safely taken with this medication if needed.

Storage Conditions Of Toprazole 40 Mg Tablets

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About Pantoprazole

• Ask your physician or pharmacist
• Visit Medscape at Information About Pantoprazole
• Visit Drugbank at Information About Pantoprazole
• Visit Drugs.com at Information About Pantoprazole
• SFDA website