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Exforge HCT 5/160/25, For High Blood Pressure - 28 Tablets
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Exforge HCT 5/160/25, Reduce Blood Pressure, Prevent Hypertension Complication - 28 Tablets
Product Name
- Exforge HCT 5/160/25, Reduce Blood Pressure, Prevent Hypertension Complication - 28 Tablets
Scientific Name
- Amlodipine 5 Mg + Valsartan 160 Mg + Hydrochlorothiazide 25 Mg Tablets
Category Of Exforge HCT 5/160/25 Tablets
- Anti-Hypertensive Drugs
Mechanism Of Action Of Valsartan, Amlodipine & Hydrochlorothiazide
- Valsartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to constrict.
- As a result, Valsartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
- Amlodipine inhibits calcium ion influx across cell membranes, with a greater effect on vascular smooth muscle cells. This causes vasodilation and a reduction in peripheral vascular resistance, thus lowering blood pressure.
- Hydrochlorothiazide inhibits sodium chloride transport in the distal convoluted tubule. More sodium is then excreted in the kidney with accompanying fluid.
- Thus it increases urine excretion, which by turn decreases blood volume and finally blood pressure.
- On long-term usage, thiazide diuretic (TZD)-mediated chronic reduction of arterial pressure is thought to occur through decreased total peripheral vascular resistance.
Therapeutic Indications Of Exforge HCT 5/160/25 Tablets
- Treating high blood pressure (hypertension) in adult patients when monotherapy with amlodipine, valsartan, or hydrochlorothiazide is not sufficient.
- High blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.
- Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Method Of Administration Of Exforge HCT 5/160/25 Tablets
- Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
- The tablets should be swallowed whole with a glass of water.
- You should try to take your daily dose at about the same time each day.
- You must continue to take the drug until your doctor tells you otherwise.
- Do not break the tablet in half
- You can take the tablet with or without food.
- The usual dose of Amlodipine/Valsartan/Hydrochlorothiazide is one tablet per day
- Depending on how you respond to the treatment, your doctor may suggest a higher or lower dose.
- Do not exceed the prescribed dose.
- Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
- If you take more than you should, talk to a doctor or go to the hospital straight away.
- If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
- Do not take a double dose (two doses at the same time) to make up for the forgotten dose.
Undesirable Side Effects Of Exforge HCT 5/160/25 Tablets
- Dizziness
- Low blood pressure (feeling of faintness, light-headedness, sudden loss of consciousness)
- Sleepiness
- Palpitations (awareness of your heartbeat)
- Flushing
- Ankle swelling (edema)
- Abdominal pain
- Stomach discomfort after a meal
- Tiredness
- Headache
- Frequent urination
- Low level of potassium in the blood
- High level of uric acid in the blood
- Low level of magnesium in the blood
- Low level of sodium in the blood
- Reduced appetite
- Nausea and vomiting
- Itchy rash and other types of rash
- Inability to achieve or maintain an erection
Pregnancy & Breastfeeding Precautions While Taking Exforge HCT 5/160/25 Tablets
- If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Non-Pharmacological Treatments & Advice To Reduce Blood Pressure
- To measure blood pressure correctly:
- Don’t eat or drink anything 30 minutes before you take your blood pressure.
- Empty your bladder before your reading.
- Sit in a comfortable chair with your back supported for at least 5 minutes before your reading.
- Put both feet flat on the ground and keep your legs uncrossed.
- Rest your arm with the cuff on a table at chest height.
- Make sure the blood pressure cuff is snug but not too tight. The cuff should be against your bare skin, not over clothing.
- Do not talk while your blood pressure is being measured.
- You will also find the following Non-Pharmacological treatments effective in blood pressure reduction:
- Lose extra pounds and watch your waistline
- Exercise regularly
- Eat a healthy diet
- Reduce sodium in your diet
- Quit smoking
- Reduce caffeine
- Reduce your stress
- Monitor your blood pressure at home using for example Beurer, Blood Pressure Monitor or Omron Blood Pressure Measuring Device
- See your doctor regularly
Warnings & Special Precautions while Taking Exforge HCT 5/160/25 Tablets
- Talk to your doctor or pharmacist before taking Amlodipine/Valsartan/Hydrochlorothiazide:
- If you have a low level of potassium or magnesium in your blood (with or without symptoms such as muscle weakness, muscle spasms, abnormal heart rhythm).
- If you have a low level of sodium in your blood (with or without symptoms such as tiredness, confusion, muscle twisting, convulsions).
- If you have a high level of calcium in your blood (with or without symptoms such as nausea, vomiting, constipation, stomach pain, frequent urination, thirst, muscle weakness, and twitching).
- If you have kidney problems, have had a kidney transplant, or if you had been told that you have a narrowing of your kidney arteries.
- If you have liver problems.
- if you have or have had heart failure or coronary artery disease, particularly if you are prescribed the maximum dose of Amlodipine/valsartan/Hydrochlorothiazide (10 mg/320 mg/25 mg).
- If you have experienced a heart attack. Follow your doctor’s instructions for the starting dose carefully. Your doctor may also check your kidney function.
- If your doctor has told you that you have a narrowing of the valves in your heart (called “aortic or mitral stenosis”) or that the thickness of your heart muscle is abnormally increased (called “obstructive hypertropic cardiomyopathy”).
- If you suffer from aldosteronism. This is a disease in which the adrenal glands make too much of the hormone aldosterone if this applies to you, the use of Amlodipine/Valsartan/Hydrochlorothiazide is not recommended.
- If you suffer from a disease called systemic lupus erythematosus (also called “lupus” or “SLE”).
- If you have diabetes (high level of sugar in your blood).
- If you have high levels of cholesterol or triglycerides in your blood.
- If you experience skin reactions such as rash after sun exposure.
- If you had an allergic reaction to other high blood pressure medicines or diuretics (a type of medicine also known as “water tablets”), especially if you suffer from asthma and allergies
- If you have been sick (vomiting or diarrhea).
- If you have experienced swelling, particularly of the face and throat, while taking other medicines (including angiotensin-converting enzyme inhibitors). If you get these symptoms, stop taking this medicine and contact your doctor straight away. You should never take this medicine again.
- If you experience dizziness and/or fainting during treatment with Amlodipine/Valsartan/Hydrochlorothiazide, tell your doctor as soon as possible
- If you experience a decrease in vision or eye pain
- If you have had skin cancer or if you develop an unexpected skin lesion during the treatment.
- Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines including vitamins & medications taken without prescription
Storage Conditions Of Exforge HCT 5/160/25 Tablets
- Store below 25°c
- Don’t refrigerate
- Keep this medicine out of the sight and reach of children.
- Store in the original package to protect from moisture.
- Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.
Normal Ranges
- Normal: Blood pressure numbers of less than 120/80 mm Hg
- Elevated: is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.
- Hypertension Stage 1: is when blood pressure consistently ranges from 130-139 systolic or 80-89 mm Hg diastolic.
- Hypertension Stage 2: is when blood pressure consistently ranges at 140/90 mm Hg or higher.
- Hypertensive crisis: This stage of high blood pressure requires medical attention. If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and then test your blood pressure again. If your readings are still unusually high, contact your doctor immediately. You could be experiencing a hypertensive crisis.
For More Information About Valsartan, Amlodipine & Hydrochlorothiazide
- Ask your physician or pharmacist
- Visit SFDA website
- Visit Medscape at Information About Valsartan, Amlodipine & Hydrochlorothiazide
- Visit Drugs.com at Information About Valsartan, Amlodipine & Hydrochlorothiazide
Size | 28 Pcs |
---|---|
Brand | EXFORGE |
Is Bonded | No |
Bonded Types | None |
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